Magnetic Resonance Images (MRI) of brains are a great example for turning 2D images into 3D structures with depth and perspective. The underlying metrics can be used for comparing images and formulating selection criteria.
Anaplastic astrocytoma
From Wikimedia
Anaplastic astrocytoma_1
Anaplastic astrocytoma_2
Bonthius A
BonthiusA_1
BonthiusA_2
Bonthius B
BonthiusB_1
BonthiusB_2